Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | CCR3 | P51677 | 3/20 | 0.57 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.51 |
| ▸ | CCR1 | P32246 | 8/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5858628 | 0.94 | DRD2 (0.61) | DRD2SLC6A4CCR3KCNA3CCR1 | |
| SCHEMBL904833 | 0.81 | CCR3 (0.57) | CCR3KCNA3CCR1 | |
| SCHEMBL904860 | 0.77 | CCR3 (0.57) | CCR3KCNA3CCR1 | |
| SCHEMBL9103936 | 0.76 | KCNA3 (0.85) | CCR3KCNA3CCR1 | |
| SCHEMBL904831 | 0.76 | CCR3 (0.64) | CCR3KCNA3CCR1 | |
| SCHEMBL7470794 | 0.75 | KCNA3 (0.85) | CCR3KCNA3CCR1 | |
| SCHEMBL904853 | 0.73 | CCR3 (0.55) | CCR3KCNA3CCR1 | |
| SCHEMBL3746308 | 0.73 | DRD2 (0.62) | DRD2SLC6A4 | |
| SCHEMBL5858616 | 0.73 | DRD2 (0.69) | DRD2SLC6A4KCNA3 | |
| SCHEMBL3752313 | 0.72 | DRD2 (0.61) | DRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143444-A2 | DIPHENYLBUTYPIPERIDINE AUTOPHAGY INDUCERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-11-17 | — | — | WO | disclosed |