Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 9/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 9/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 9/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.49 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1855782 | 0.76 | ADRA1D (0.58) | ADRA1DADRA1AADRA1BHTR2AHTR7 | |
| SCHEMBL27048956 | 0.76 | ADRA1D (0.60) | ADRA1DADRA1AADRA1BHTR2AHTR7 | |
| SCHEMBL9103936 | 0.74 | KCNA3 (0.85) | CCR3KCNA3CCR1 | |
| SCHEMBL1861402 | 0.74 | ADRA1D (0.56) | ADRA1DADRA1AADRA1BHTR2AHTR7 | |
| SCHEMBL904831 | 0.74 | CCR3 (0.64) | CCR3KCNA3CCR1 | |
| SCHEMBL904860 | 0.73 | CCR3 (0.57) | CCR3KCNA3CCR1 | |
| SCHEMBL904833 | 0.73 | CCR3 (0.57) | CCR3HTR2AHTR7KCNA3CCR1 | |
| SCHEMBL904859 | 0.73 | DRD2 (0.58) | CCR3KCNA3CCR1 | |
| SCHEMBL7470794 | 0.73 | KCNA3 (0.85) | CCR3KCNA3CCR1 | |
| SCHEMBL904904 | 0.73 | ADRA1A (0.66) | ADRA1DADRA1AADRA1BHTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143444-A2 | DIPHENYLBUTYPIPERIDINE AUTOPHAGY INDUCERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-11-17 | — | — | WO | disclosed |