Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 3/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
| ▸ | HTR1F | P30939 | 2/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.32 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.32 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19981007 | 0.86 | P2RY6 (0.34) | P2RY2ROCK2P2RY6P2RY14P2RY4 | |
| SCHEMBL14946367 | 0.86 | P2RY6 (0.34) | P2RY2ROCK2P2RY6P2RY14P2RY4 | |
| SCHEMBL10459464 | 0.86 | P2RY6 (0.34) | P2RY2ROCK2P2RY6P2RY14P2RY4 | |
| SCHEMBL20459987 | 0.86 | P2RY6 (0.34) | P2RY2ROCK2P2RY6P2RY14P2RY4 | |
| SCHEMBL20215740 | 0.86 | P2RY6 (0.34) | P2RY2ROCK2P2RY6P2RY14P2RY4 | |
| SCHEMBL1937265 | 0.86 | P2RY6 (0.34) | P2RY2ROCK2P2RY6P2RY14P2RY4 | |
| SCHEMBL6365808 | 0.82 | P2RY6 (0.47) | P2RY2RAB9AP2RY6P2RY14P2RY4 | |
| SCHEMBL13151571 | 0.82 | P2RY6 (0.47) | P2RY2RAB9AP2RY6P2RY14P2RY4 | |
| SCHEMBL13672352 | 0.82 | P2RY6 (0.47) | P2RY2RAB9AP2RY6P2RY14P2RY4 | |
| SCHEMBL9048255 | 0.82 | RAB9A (0.33) | P2RY2ROCK2TSPOHTR1FHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |