Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | PTGIR | P43119 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048139 | 0.91 | DRD4 (0.47) | DRD4PTGIRNR1H3 | |
| SCHEMBL9048631 | 0.87 | PTGIR (0.54) | DRD4PTGIR | |
| SCHEMBL9427064 | 0.84 | LMNA (0.45) | DRD4PTGIRNR1H3 | |
| SCHEMBL9046170 | 0.82 | PTGIR (0.44) | DRD4PTGIRNR1H3 | |
| SCHEMBL9048617 | 0.81 | DRD4 (0.42) | DRD4EPHX2CNR1MTNR1AMTNR1B | |
| SCHEMBL9048933 | 0.79 | PTGIR (0.52) | DRD4PTGIRNR1H3 | |
| SCHEMBL9568169 | 0.79 | PRMT5 (0.52) | EPHX2CNR1MTNR1AMTNR1BCNR2 | |
| SCHEMBL9051667 | 0.78 | PTGIR (0.44) | DRD4PTGIR | |
| SCHEMBL8858437 | 0.77 | PTGIR (0.56) | DRD4PTGIR | |
| SCHEMBL9050478 | 0.77 | PTGIR (0.39) | DRD4PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |