SCHEMBL9048933

SCHEMBL9048933

O=C(CO)Oc1cccc2c1CCCC2C(=O)NN(c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PTGIR P43119 3/20 0.52
DRD4 P21917 1/20 0.42
ACHE P22303 3/20 0.38
NR1H3 Q13133 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9046416 0.85 PTGIR (0.70) PTGIRDRD4
SCHEMBL9427260 0.83 PTGIR (0.76) PTGIR
SCHEMBL9427411 0.83 PTGIR (0.48) PTGIRACHE
SCHEMBL9427064 0.82 LMNA (0.45) PTGIRDRD4NR1H3
SCHEMBL9048139 0.82 DRD4 (0.47) PTGIRDRD4NR1H3
SCHEMBL9046170 0.80 PTGIR (0.44) PTGIRDRD4ACHENR1H3
SCHEMBL9051667 0.79 PTGIR (0.44) PTGIRDRD4
SCHEMBL9048623 0.79 DRD4 (0.49) PTGIRDRD4NR1H3
SCHEMBL9047483 0.79 ACHE (0.40) PTGIRDRD4ACHENR1H3
SCHEMBL9048927 0.78 PTGIR (0.43) PTGIRDRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0542203-B1 Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists ONO PHARMACEUTICAL CO (JP) 1996-07-03 EP claimed