Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046310 | 0.86 | PTGIR (0.61) | PTGIRDRD4TBXAS1MEN1KMT2A | |
| SCHEMBL9427064 | 0.80 | LMNA (0.45) | PTGIRDRD4 | |
| SCHEMBL9048139 | 0.80 | DRD4 (0.47) | PTGIRDRD4 | |
| SCHEMBL9050562 | 0.79 | NPSR1 (0.43) | PTGIRDRD4ALDH1A1NPSR1 | |
| SCHEMBL9048933 | 0.79 | PTGIR (0.52) | PTGIRDRD4 | |
| SCHEMBL9046170 | 0.78 | PTGIR (0.44) | PTGIRDRD4 | |
| SCHEMBL9048623 | 0.78 | DRD4 (0.49) | PTGIRDRD4 | |
| SCHEMBL9427127 | 0.76 | PTGIR (0.43) | PTGIRDRD4TBXAS1 | |
| SCHEMBL9050347 | 0.75 | PTGIR (0.48) | PTGIRTBXAS1 | |
| SCHEMBL9047483 | 0.75 | ACHE (0.40) | PTGIRDRD4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |