Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 9/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045869 | 0.83 | LMNA (0.51) | EPHX2LMNA | |
| SCHEMBL9568170 | 0.82 | P2RX7 (0.45) | EPHX2P2RX7GHSRLMNAF2 | |
| SCHEMBL9046598 | 0.82 | POLB (0.41) | PTGIREPHX2P2RX7GHSR | |
| SCHEMBL9048858 | 0.82 | PTGIR (0.46) | PTGIR | |
| SCHEMBL9048642 | 0.80 | PTGIR (0.62) | PTGIR | |
| SCHEMBL9048637 | 0.80 | PTGIR (0.45) | PTGIREPHX2S1PR5 | |
| SCHEMBL9046164 | 0.76 | PTGIR (0.37) | PTGIR | |
| SCHEMBL9048971 | 0.73 | PTGIR (0.37) | PTGIRLMNA | |
| SCHEMBL9427232 | 0.70 | PTGIR (0.36) | PTGIR | |
| SCHEMBL9048118 | 0.70 | PTGIR (0.36) | PTGIRS1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |