Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 12/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048642 | 0.86 | PTGIR (0.62) | PTGIRTBXAS1 | |
| SCHEMBL9045875 | 0.85 | LMNA (0.47) | PTGIRCA1CA2ACHEEPHX2 | |
| SCHEMBL9048863 | 0.84 | PTGIR (0.51) | PTGIRTBXAS1 | |
| SCHEMBL9048633 | 0.80 | PTGIR (0.38) | PTGIREPHX2S1PR5 | |
| SCHEMBL9568170 | 0.80 | P2RX7 (0.45) | EPHX2MTNR1AMTNR1B | |
| SCHEMBL9046170 | 0.78 | PTGIR (0.44) | PTGIRACHE | |
| SCHEMBL9048978 | 0.76 | PTGIR (0.41) | PTGIRACHE | |
| SCHEMBL9427236 | 0.74 | PTGIR (0.43) | PTGIRCA1CA2ACHES1PR5 | |
| SCHEMBL9048138 | 0.73 | PTGIR (0.52) | PTGIRTBXAS1 | |
| SCHEMBL9048119 | 0.73 | PTGIR (0.42) | PTGIRCA1CA2ACHES1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |