Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | KRAS | P01116 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049643 | 0.97 | HSD11B1 (0.46) | HSD11B1CHRM2KRAS | |
| SCHEMBL9049262 | 0.94 | CHRM2 (0.48) | HSD11B1CHRM2 | |
| Oxalic Acid SCHEMBL9051385 | 0.92 | HSD11B1 (0.39) | HSD11B1CHRM2 | |
| SCHEMBL8790855 | 0.90 | HSD11B1 (0.46) | HSD11B1CHRM2KRAS | |
| Oxalic Acid SCHEMBL9050512 | 0.88 | HSD11B1 (0.41) | HSD11B1CHRM2 | |
| Oxalic Acid SCHEMBL9050722 | 0.85 | CHRM2 (0.42) | HSD11B1CHRM2 | |
| Oxalic Acid SCHEMBL8790622 | 0.82 | HSD11B1 (0.41) | HSD11B1CHRM2 | |
| SCHEMBL10588564 | 0.76 | EPHX2 (0.32) | — | |
| SCHEMBL9050429 | 0.75 | HCRTR1 (0.32) | — | |
| SCHEMBL9786022 | 0.74 | HSD11B1 (0.33) | HSD11B1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287356-B1 | Bridgehead substituted azabicyclic derivatives | BEECHAM GROUP PLC (GB) | 1996-01-24 | — | — | EP | claimed |
| EP-0287356-A2 | Bridgehead substituted azabicyclic derivatives | BEECHAM GROUP PLC (GB) | 1988-10-19 | — | — | EP | claimed |