Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HTR2B | P41595 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.56 |
| ▸ | MLNR | O43193 | 1/20 | 0.56 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.56 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | USP1 | O94782 | 1/20 | 0.56 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.56 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904921 | 0.89 | HTR2B (0.51) | KMT2AHTR2BKDM4EMEN1SLC22A2 | |
| SCHEMBL7501230 | 0.86 | HTR2B (0.61) | KMT2AHTR2BALDH1A1CYP2D6TSHR | |
| SCHEMBL17888859 | 0.79 | HTR2B (0.60) | KMT2AHTR2BHRH1CHRNA7 | |
| SCHEMBL7533221 | 0.79 | HTR2B (0.60) | KMT2AHTR2BALDH1A1TSHRNPSR1 | |
| SCHEMBL904908 | 0.77 | GAA (0.49) | KMT2AHTR2BKDM4EMEN1SLC22A2 | |
| SCHEMBL10395865 | 0.77 | DRD3 (0.54) | KMT2AHTR2BKDM4EMEN1SLC22A2 | |
| SCHEMBL904827 | 0.77 | LMNA (0.55) | KMT2AALDH1A1LMNAMAPTDRD2 | |
| SCHEMBL17888861 | 0.76 | HTR2B (0.62) | KMT2AHTR2BCHRNA7 | |
| SCHEMBL904821 | 0.76 | ADRA1D (0.64) | CYP2D6SLC6A4 | |
| SCHEMBL9372446 | 0.76 | HTR2A (0.52) | KMT2AHTR2BKDM4EMEN1SLC22A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143444-A2 | DIPHENYLBUTYPIPERIDINE AUTOPHAGY INDUCERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-11-17 | — | — | WO | disclosed |