Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | DRD4 | P21917 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.51 |
| ▸ | UBE2M | P61081 | 1/20 | 0.48 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6399328 | 0.83 | DRD2 (0.65) | LMNASMN1; SMN2MAPTTSHRHTT | |
| SCHEMBL14463703 | 0.79 | DRD2 (0.63) | LMNASMN1; SMN2MAPTDRD2DRD4 | |
| SCHEMBL7533466 | 0.79 | DRD2 (0.60) | LMNASMN1; SMN2MAPTTSHRHTT | |
| SCHEMBL8025525 | 0.78 | DRD2 (0.58) | LMNASMN1; SMN2MAPTTSHRHTT | |
| SCHEMBL5024739 | 0.77 | DRD4 (0.57) | SMN1; SMN2DRD2DRD4ALDH1A1HTR2A | |
| SCHEMBL904877 | 0.77 | KMT2A (0.56) | LMNASMN1; SMN2MAPTTSHRHTT | |
| SCHEMBL904908 | 0.77 | GAA (0.49) | LMNASMN1; SMN2MAPTTSHRHTT | |
| SCHEMBL11094512 | 0.77 | DRD2 (0.48) | LMNASMN1; SMN2MAPTTSHRHTT | |
| Hydrochloric Acid SCHEMBL10990534 | 0.76 | DRD2 (0.48) | LMNASMN1; SMN2MAPTTSHRHTT | |
| SCHEMBL31145168 | 0.75 | DRD2 (0.58) | LMNASMN1; SMN2MAPTTSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143444-A2 | DIPHENYLBUTYPIPERIDINE AUTOPHAGY INDUCERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-11-17 | — | — | WO | disclosed |