Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8007692 | 0.83 | ALDH1A1 (0.38) | EGFROPRM1MEN1KMT2ALDHA | |
| SCHEMBL6604162 | 0.83 | ALDH1A1 (0.38) | EGFROPRM1MEN1KMT2ALDHA | |
| SCHEMBL6606008 | 0.83 | ASAH1 (0.37) | EGFRMAOBNPC1ALDH1A1CYP2C9 | |
| SCHEMBL8008694 | 0.80 | EGFR (0.35) | EGFRTAAR1MEN1KMT2ALDHA | |
| SCHEMBL8346206 | 0.80 | EGFR (0.35) | EGFRTAAR1MEN1KMT2ALDHA | |
| SCHEMBL6175624 | 0.79 | EGFR (0.38) | EGFRLDHACYP1A2 | |
| SCHEMBL6605717 | 0.78 | EGFR (0.38) | EGFROPRM1NPC1KMT2ALDHA | |
| SCHEMBL6302764 | 0.77 | OPRM1 (0.35) | DAOOPRM1OPRD1OPRK1TAAR1 | |
| SCHEMBL8341314 | 0.77 | OPRK1 (0.39) | OPRM1OPRD1OPRK1TAAR1 | |
| SCHEMBL8008514 | 0.77 | OPRK1 (0.39) | OPRM1OPRD1OPRK1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729464-A1 | 5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE, DAVIS & COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |