Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2657141 | 0.76 | ALDH1A1 (0.46) | SMN1; SMN2 | |
| SCHEMBL9098198 | 0.73 | MYC (0.59) | MYCWDR5NOS1CDK2BACE1 | |
| SCHEMBL9045818 | 0.72 | MYC (0.43) | MYCWDR5NOS1CDK2 | |
| SCHEMBL9045577 | 0.69 | RAB9A (0.42) | MYCWDR5NOS1CDK2BACE1 | |
| SCHEMBL9097160 | 0.66 | ALDH1A1 (0.54) | MYCSMN1; SMN2 | |
| SCHEMBL9049909 | 0.66 | MYC (0.43) | MYCWDR5NOS1CDK2 | |
| SCHEMBL28436563 | 0.66 | MYC (0.43) | MYCWDR5NOS1CDK2BACE1 | |
| SCHEMBL702948 | 0.66 | — | — | |
| SCHEMBL9033273 | 0.65 | POLB (0.35) | — | |
| SCHEMBL9098094 | 0.65 | MYC (0.46) | MYCWDR5NOS1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412404-B1 | Thiazole derivatives, processes for production thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-01-31 | — | — | EP | disclosed |