Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | TXN | P10599 | 1/20 | 0.33 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9098198 | 0.77 | MYC (0.59) | MYCWDR5NOS1CDK2ALDH1A1 | |
| SCHEMBL9048819 | 0.72 | MYC (0.40) | MYCWDR5NOS1CDK2 | |
| SCHEMBL1740306 | 0.72 | TXN (0.45) | MYCTXNTXNRD1GCKFDPS | |
| SCHEMBL1607000 | 0.71 | MYC (0.48) | MYCWDR5NOS1CDK2ALDH1A1 | |
| SCHEMBL9047618 | 0.70 | CCNE1 (0.49) | CDK2GCK | |
| SCHEMBL9097160 | 0.69 | ALDH1A1 (0.54) | MYCTXNALDH1A1HPGDALOX15 | |
| SCHEMBL9048249 | 0.68 | NOS1 (0.46) | MYCWDR5NOS1CDK2ALDH1A1 | |
| SCHEMBL9097506 | 0.67 | CYP3A4 (0.46) | MYCWDR5ALDH1A1HPGD | |
| SCHEMBL9100372 | 0.67 | FBP1 (0.45) | MYCWDR5NOS1CDK2FDPS | |
| SCHEMBL11201564 | 0.67 | FBP1 (0.42) | MYCTXNTXNRD1GCKFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412404-B1 | Thiazole derivatives, processes for production thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-01-31 | — | — | EP | disclosed |
| CN-1027370-C | Process for preparing thiazole derivatives | FUJISAWA FARMACEUTICAL CO LTD (JP) | 1995-01-11 | — | — | CN | disclosed |
| US-5369107-A | Thiazole derivatives, processes for production thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-29 | — | — | US | disclosed |
| US-5256675-A | Antirheumatic agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-26 | — | — | US | disclosed |
| CN-1049337-A | Thiazole derivative prepares their method, and the medicinal compositions that contains them | FUJISAWA PHARMACEUTICAL CO (JP) | 1991-02-20 | — | — | CN | disclosed |
| EP-0412404-A2 | Thiazole derivatives, processes for production thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-13 | — | — | EP | disclosed |