Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | CASP1 | P29466 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8120835 | 0.94 | TSHR (0.39) | TSHRCYP3A4ALOX15MAPK1VCP | |
| SCHEMBL9050816 | 0.90 | TLR7 (0.44) | TLR7TSHRLMNACASP1SMN1; SMN2 | |
| SCHEMBL8121831 | 0.84 | USP1 (0.35) | TSHRVCPLMNACASP1SMN1; SMN2 | |
| SCHEMBL8122097 | 0.84 | KDM4E (0.36) | TLR7CYP3A4MAPK1POLBADORA2A | |
| SCHEMBL8123905 | 0.83 | SMN1; SMN2 (0.38) | TLR7TSHRVCPLMNACASP1 | |
| SCHEMBL8123022 | 0.83 | SMN1; SMN2 (0.38) | TSHRVCPLMNACASP1SMN1; SMN2 | |
| SCHEMBL8121124 | 0.82 | KDM4E (0.36) | TLR7CYP3A4MAPK1POLBADORA2A | |
| SCHEMBL8112838 | 0.80 | LMNA (0.36) | TLR7TSHRCYP3A4VCPLMNA | |
| SCHEMBL8115033 | 0.79 | TLR7 (0.42) | TLR7LMNASMN1; SMN2POLBHRH2 | |
| SCHEMBL8114890 | 0.75 | TSHR (0.43) | TLR7TSHRCYP3A4ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708773-A1 | FUSED CYCLOALKYLIMIDAZOPYRIDINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995002598-A1 | FUSED CYCLOALKYLIMIDAZOPYRIDINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-01-26 | — | — | WO | disclosed |