Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048835 | 0.94 | TLR7 (0.39) | TSHRCYP3A4ALOX15MAPK1VCP | |
| SCHEMBL8121831 | 0.90 | USP1 (0.35) | TSHRVCPSMN1; SMN2LMNACASP1 | |
| SCHEMBL8123905 | 0.89 | SMN1; SMN2 (0.38) | TSHRVCPSMN1; SMN2LMNACASP1 | |
| SCHEMBL8123022 | 0.89 | SMN1; SMN2 (0.38) | TSHRVCPSMN1; SMN2LMNACASP1 | |
| SCHEMBL8112838 | 0.85 | LMNA (0.36) | TSHRCYP3A4VCPSMN1; SMN2LMNA | |
| SCHEMBL9050816 | 0.84 | TLR7 (0.44) | TSHRSMN1; SMN2LMNACASP1NPSR1 | |
| SCHEMBL8112841 | 0.84 | SPR (0.32) | TSHRVCPSMN1; SMN2LMNACASP1 | |
| SCHEMBL8114890 | 0.80 | TSHR (0.43) | TSHRCYP3A4ALOX15MAPK1SMN1; SMN2 | |
| SCHEMBL8122097 | 0.74 | KDM4E (0.36) | CYP3A4MAPK1NPC1KDM4EGAA | |
| SCHEMBL8121124 | 0.73 | KDM4E (0.36) | CYP3A4MAPK1HTTHSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708773-B1 | FUSED CYCLOALKYLIMIDAZOPYRIDINES | MINNESOTA MINING & MFG (US) | 2000-10-04 | — | — | EP | disclosed |
| US-5886006-A | VIRICIDES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-03-23 | — | — | US | disclosed |
| US-5648516-A | INTERFERON BIOSYNTHESIS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-07-15 | — | — | US | disclosed |
| US-5627281-A | CHEMCAL INTERMEDIATES FOR VIRICIDES BY INDUCING SYNTHESIS OF INTERFERONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-05-06 | — | — | US | disclosed |
| EP-0708773-A1 | FUSED CYCLOALKYLIMIDAZOPYRIDINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-05-01 | — | — | EP | disclosed |
| US-5444065-A | Viricides | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-08-22 | — | — | US | disclosed |
| WO-1995002598-A1 | FUSED CYCLOALKYLIMIDAZOPYRIDINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-01-26 | — | — | WO | disclosed |
| US-5352784-A | Viricides; immunomodulators | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-10-04 | — | — | US | disclosed |