Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047610 | 0.89 | MEN1 (0.44) | MEN1KMT2AADORA3TSHRPOLB | |
| SCHEMBL9049795 | 0.88 | HDAC1 (0.41) | MAPTTHRBHPGDSMN1; SMN2HDAC1 | |
| SCHEMBL9047688 | 0.83 | SMN1; SMN2 (0.45) | MEN1KMT2AADORA3TSHRPOLB | |
| SCHEMBL9048519 | 0.77 | CCR2 (0.42) | PTGDR2 | |
| SCHEMBL9049224 | 0.74 | MEN1 (0.39) | MEN1KMT2AGRIN1GRIN2BTSHR | |
| SCHEMBL9049151 | 0.72 | MEN1 (0.46) | MEN1KMT2AADORA3TSHRPOLB | |
| SCHEMBL9048660 | 0.71 | AKR1A1 (0.49) | MEN1KMT2ATP53MAPTSMN1; SMN2 | |
| SCHEMBL9050328 | 0.69 | TSHR (0.51) | MEN1KMT2ATSHRPOLBMAPT | |
| SCHEMBL9057858 | 0.68 | POLB (0.57) | MEN1KMT2AADORA3TSHRPOLB | |
| SCHEMBL10487890 | 0.68 | MEN1 (0.47) | MEN1KMT2AGRIN1GRIN2BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456835-B1 | QUINAZOLINE-3-ALKANOIC ACID DERIVATIVE, SALT THEREOF, AND PRODUCTION THEREOF | KYORIN SEIYAKU KK (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-5234928-A | Inhibit platelet aggregation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0456835-A1 | QUINAZOLINE-3-ALKANOIC ACID DERIVATIVE, SALT THEREOF, AND PRODUCTION THEREOF | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1991-11-21 | — | — | EP | disclosed |