Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1A1 | P14550 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RHEB | Q15382 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047688 | 0.89 | SMN1; SMN2 (0.45) | AKR1A1AKR1B1MEN1KMT2ALMNA | |
| SCHEMBL9048519 | 0.85 | CCR2 (0.42) | AKR1A1AKR1B1PTGDR2RHEB | |
| SCHEMBL9049795 | 0.82 | HDAC1 (0.41) | AKR1B1PTGDR2SMN1; SMN2MAPT | |
| SCHEMBL9047096 | 0.78 | KMT2A (0.55) | AKR1A1AKR1B1MEN1KMT2APTGDR2 | |
| SCHEMBL9047610 | 0.74 | MEN1 (0.44) | MEN1KMT2APTGDR2LMNASMN1; SMN2 | |
| SCHEMBL9047397 | 0.72 | NR4A2 (0.48) | AKR1A1AKR1B1MEN1KMT2APTGDR2 | |
| SCHEMBL11269563 | 0.70 | LMNA (0.62) | AKR1A1AKR1B1MEN1KMT2APTGDR2 | |
| SCHEMBL9056716 | 0.70 | AKR1B1 (0.78) | AKR1A1AKR1B1MEN1KMT2APTGDR2 | |
| SCHEMBL10488016 | 0.70 | AKR1A1 (0.60) | AKR1A1AKR1B1MEN1KMT2ALMNA | |
| SCHEMBL9047901 | 0.69 | LMNA (0.52) | AKR1A1AKR1B1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456835-B1 | QUINAZOLINE-3-ALKANOIC ACID DERIVATIVE, SALT THEREOF, AND PRODUCTION THEREOF | KYORIN SEIYAKU KK (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-5234928-A | Inhibit platelet aggregation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0456835-A1 | QUINAZOLINE-3-ALKANOIC ACID DERIVATIVE, SALT THEREOF, AND PRODUCTION THEREOF | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1991-11-21 | — | — | EP | disclosed |