SCHEMBL904899

SCHEMBL904899

N#CC(CCCN1CCC(N2CCc3ccccc32)CC1)(c1ccccc1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CCR3 P51677 3/20 0.59
KCNA3 P22001 4/20 0.53
CCR1 P32246 7/20 0.49
RAB9A P51151 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL904831 0.82 CCR3 (0.64) CCR3KCNA3CCR1RAB9ANPSR1
SCHEMBL14349454 0.81 OPRM1 (0.53)
SCHEMBL14282272 0.80 OPRM1 (0.52)
SCHEMBL9103936 0.78 KCNA3 (0.85) CCR3KCNA3CCR1
SCHEMBL7470794 0.77 KCNA3 (0.85) CCR3KCNA3CCR1RAB9ANPSR1
SCHEMBL5871299 0.74 ACHE (0.54) CCR3
SCHEMBL5871358 0.73 OPRM1 (0.51)
Fluorobenzene SCHEMBL27495584 0.73 DRD3 (0.47)
SCHEMBL904833 0.72 CCR3 (0.57) CCR3KCNA3CCR1
SCHEMBL904860 0.72 CCR3 (0.57) CCR3KCNA3CCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011143444-A2 DIPHENYLBUTYPIPERIDINE AUTOPHAGY INDUCERS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2011-11-17 WO disclosed