SCHEMBL9049017

SCHEMBL9049017

O=C(O)N1CCC(N2CCCCC2=O)CC1

nearest known ligand 0.65

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
VNN1 O95497 3/20 0.43
F10 P00742 3/20 0.42
KDM5A P29375 1/20 0.41
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
KMT2A Q03164 1/20 0.38
NPY5R Q15761 1/20 0.38
L3MBTL3 Q96JM7 3/20 0.37
L3MBTL1 Q9Y468 3/20 0.37
DPP4 P27487 1/20 0.37
DPP8 Q6V1X1 1/20 0.37
DPP9 Q86TI2 1/20 0.37
LTA4H P09960 1/20 0.37
MBTD1 Q05BQ5 1/20 0.37
TP53BP1 Q12888 1/20 0.37
L3MBTL4 Q8NA19 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21597921 0.98 F10 (0.43) VNN1F10KDM5ANPC1RAB9A
SCHEMBL15264280 0.95 KDM5A (0.44) VNN1F10KDM5ANPC1RAB9A
SCHEMBL30341931 0.88 KMT2A (0.40) VNN1F10KDM5ANPC1RAB9A
SCHEMBL16530402 0.87 KMT2A (0.38) VNN1F10KDM5ANPC1RAB9A
SCHEMBL293570 0.85 VNN1 (0.42) VNN1F10KDM5ANPC1RAB9A
SCHEMBL1974787 0.83 L3MBTL3 (0.37) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL29145778 0.82 VNN1 (0.43) VNN1F10KDM5ANPC1RAB9A
SCHEMBL1973070 0.81 NOS3 (0.50) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL2176405 0.81 DPP4 (0.43) VNN1F10NPY5RDPP4DPP8
SCHEMBL29145744 0.81 VNN1 (0.42) VNN1F10KDM5ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2828253-A1 CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME Abide Therapeutics, Inc. (US) 2015-01-28 EP claimed
WO-2013142307-A1 CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME ABIDE THERAPEUTICS (US) 2013-09-26 WO claimed
EP-2828253-A1 CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME Abide Therapeutics, Inc. (US) 2015-01-28 EP disclosed
WO-2013142307-A1 CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME ABIDE THERAPEUTICS (US) 2013-09-26 WO disclosed
EP-0726893-A1 NOVEL 4-PIPERIDINYL SUBSTITUTED LACTAMES AS NEUROKININ 2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF ASTHMA ZENECA LIMITED (GB) 1996-08-21 EP disclosed
WO-1995012577-A1 NOVEL 4-PIPERIDINYL SUBSTITUTED LACTAMES AS NEUROKININ 2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF ASTHMA ZENECA LIMITED (GB) 1995-05-11 WO disclosed