Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049033 | 0.96 | CHRM2 (0.42) | CHRM2CHRM4CHRM1CHRM3PKM | |
| SCHEMBL8790912 | 0.91 | CHRM2 (0.34) | CHRM2CHRM4CHRM1CHRM3PKM | |
| SCHEMBL9050123 | 0.86 | CHRM2 (0.36) | CHRM2CHRM4CHRM1CHRM3PKM | |
| SCHEMBL3951763 | 0.79 | CHRM2 (0.39) | CHRM2CHRM4CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL9051821 | 0.77 | CHRM2 (0.38) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL205678 | 0.77 | CHRM2 (0.38) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL31731969 | 0.76 | CHRM2 (0.44) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL205297 | 0.76 | CHRM2 (0.44) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL8790867 | 0.74 | CHRM2 (0.35) | CHRM2CHRM4CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL2421629 | 0.74 | CHRM2 (0.42) | CHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5244907-A | Treatment of serotonin imbalance, increase in gastric motility, antiemetics, antiarrhythmia agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-09-14 | — | — | US | disclosed |
| US-5190953-A | 1-azabicyclo(3.2.1.)octan-5-ylmethyl- or 1-azabicyclo(3.3.1) nonan-5-ylmethyl derivatives of carboxamides, thiocarboxamides or esters, thioesters | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-03-02 | — | — | US | disclosed |