Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1770547 | 0.77 | MAOA (0.38) | ATMAVPR1ABTN3A1 | |
| SCHEMBL1712501 | 0.77 | NPC1 (0.45) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL3966940 | 0.73 | ATM (0.47) | GAAATMHTTDRD4SLC6A4 | |
| SCHEMBL27209008 | 0.73 | ATM (0.47) | GAAATMHTTDRD4SLC6A4 | |
| SCHEMBL4679891 | 0.72 | DUT (0.36) | GAAATMMAPTL3MBTL1 | |
| SCHEMBL4212982 | 0.71 | SMN1; SMN2 (0.52) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL4212984 | 0.71 | SMN1; SMN2 (0.52) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL8884743 | 0.71 | BTN3A1 (0.35) | AVPR1ABTN3A1MAPTHPGDPOLB | |
| SCHEMBL30762084 | 0.70 | PRSS1 (0.35) | GAAHTTBTN3A1MAPTHPGD | |
| SCHEMBL13298224 | 0.70 | GAA (0.48) | GAAATMHTTDRD4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555068-B1 | Oxime derivatives as 5-lipoxygenase inhibitors | ZENECA LTD (GB) | 1996-04-10 | — | — | EP | disclosed |
| EP-0555068-A1 | Oxime derivatives as 5-lipoxygenase inhibitors | ZENECA LIMITED (GB) | 1993-08-11 | — | — | EP | disclosed |