Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.45 |
| ▸ | CCR5 | P51681 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | HTR2C | P28335 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904826 | 0.87 | HTR2A (0.58) | SIGMAR1SLC6A2SLC6A4KCNH2OPRM1 | |
| SCHEMBL904949 | 0.83 | SIGMAR1 (0.46) | SIGMAR1SLC6A2SLC6A4KCNH2OPRM1 | |
| SCHEMBL904847 | 0.81 | HTR2A (0.54) | SIGMAR1SLC6A2SLC6A4KCNH2OPRM1 | |
| SCHEMBL10361581 | 0.74 | CHRM2 (0.46) | SIGMAR1SLC6A2SLC6A4KCNH2OPRM1 | |
| SCHEMBL904889 | 0.72 | ADRA1D (0.60) | SLC6A4CYP2D6KMT2AADRA1D | |
| SCHEMBL904921 | 0.72 | HTR2B (0.51) | SIGMAR1SLC6A2SLC6A4KCNH2OPRM1 | |
| SCHEMBL904876 | 0.71 | HTR2A (0.51) | SIGMAR1SLC6A2SLC6A4KCNH2OPRM1 | |
| SCHEMBL904858 | 0.71 | HTR2A (0.51) | SIGMAR1SLC6A2SLC6A4KCNH2OPRM1 | |
| SCHEMBL904831 | 0.70 | CCR3 (0.64) | RAB9ANPSR1KCNA3CCR3 | |
| Hydrochloric Acid SCHEMBL7875692 | 0.70 | KCNH2 (0.54) | SIGMAR1SLC6A2SLC6A4KCNH2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143444-A2 | DIPHENYLBUTYPIPERIDINE AUTOPHAGY INDUCERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-11-17 | — | — | WO | disclosed |