Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | MTR | Q99707 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 6/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904839 | 0.88 | DRD3 (0.54) | SIGMAR1MTROPRM1OPRL1HTR1A | |
| SCHEMBL904928 | 0.83 | SIGMAR1 (0.50) | SIGMAR1MTROPRM1OPRL1HTR1A | |
| SCHEMBL5870875 | 0.81 | OPRM1 (0.43) | SIGMAR1OPRM1OPRL1OPRK1DRD3 | |
| SCHEMBL14349454 | 0.79 | OPRM1 (0.53) | OPRM1OPRL1OPRK1DRD3KCNH2 | |
| SCHEMBL5871383 | 0.79 | DRD3 (0.51) | SIGMAR1DRD3CYP1A2DRD2HTR2A | |
| SCHEMBL14282272 | 0.78 | OPRM1 (0.52) | OPRM1OPRL1OPRK1DRD3OPRD1 | |
| SCHEMBL3881201 | 0.74 | OPRM1 (0.56) | SIGMAR1OPRM1OPRL1HTR1AOPRK1 | |
| Fluorobenzene SCHEMBL27495584 | 0.73 | DRD3 (0.47) | SIGMAR1OPRM1OPRL1OPRK1DRD3 | |
| SCHEMBL904899 | 0.72 | CCR3 (0.59) | RAB9ANPSR1 | |
| SCHEMBL5871299 | 0.72 | ACHE (0.54) | SIGMAR1OPRM1OPRL1OPRK1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143444-A2 | DIPHENYLBUTYPIPERIDINE AUTOPHAGY INDUCERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-11-17 | — | — | WO | disclosed |