Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049171 | 0.91 | KCNH2 (0.34) | KCNH2 | |
| SCHEMBL9096542 | 0.91 | KCNH2 (0.42) | KCNH2ALDH1A1POLBCHRM2CHRM1 | |
| SCHEMBL9046791 | 0.87 | ALDH1A1 (0.43) | KCNH2ALDH1A1POLBCHRM2CHRM1 | |
| SCHEMBL9048740 | 0.83 | ADRB2 (0.40) | KCNH2ALDH1A1POLBCHRM2CHRM1 | |
| SCHEMBL9048177 | 0.83 | KCNH2 (0.36) | KCNH2ALDH1A1POLBCHRM2CHRM1 | |
| SCHEMBL9045493 | 0.83 | KDM4E (0.44) | ALDH1A1 | |
| SCHEMBL8083134 | 0.82 | KCNH2 (0.42) | KCNH2ALDH1A1POLBOPRM1 | |
| SCHEMBL9046294 | 0.81 | MEN1 (0.42) | KCNH2ALDH1A1POLBOPRM1 | |
| SCHEMBL8092759 | 0.78 | ALDH1A1 (0.54) | KCNH2ALDH1A1POLBCHRM2CHRM1 | |
| SCHEMBL9047410 | 0.77 | ALDH1A1 (0.42) | KCNH2ALDH1A1POLBCHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588166-B1 | Antibacterial 7-isoindolinyl-quinolone and naphthyridone derivatives | BAYER AG (DE) | 1996-06-05 | — | — | EP | disclosed |
| EP-0588166-A2 | Antibacterial 7-isoindolinyl-quinolone and naphthyridone derivatives | BAYER AG (DE) | 1994-03-23 | — | — | EP | disclosed |