Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.40 |
| ▸ | PDE4A | P27815 | 3/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038562 | 0.85 | ADORA2A (0.43) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL9037741 | 0.81 | ADORA2B (0.40) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL9037775 | 0.80 | ADORA2B (0.40) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL9038343 | 0.79 | ADORA2A (0.39) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL9037887 | 0.77 | PDE4B (0.45) | ADORA2BPDE4BADORA1KDM4EALDH1A1 | |
| SCHEMBL9039917 | 0.76 | ADORA2B (0.40) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL9038196 | 0.76 | ADORA2A (0.45) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL6644063 | 0.76 | ADORA2A (0.49) | ADORA2AADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL9038617 | 0.75 | HDAC1 (0.44) | ADORA1KDM4EALDH1A1HPGD | |
| SCHEMBL9039306 | 0.71 | PDE4B (0.43) | ADORA2AADORA2BPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696590-A1 | Pyrido[2,3-d]pyrimidine derivatives, their preparation and their use as anti-asthma agents | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |