N,N-Dimethylethanaminium

N,N-Dimethylethanaminium

SCHEMBL9049895

CCN(C)C.O=P(O)(O)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of N,N-Dimethylethanaminium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 4/20 0.46
MMP2 P08253 4/20 0.46
MMP1 P03956 3/20 0.46
MMP3 P08254 3/20 0.46
MMP8 P22894 3/20 0.46
CA2 P00918 1/20 0.38
USP2 O75604 1/20 0.38
ALOX15 P16050 1/20 0.38
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
LAP3 P28838 1/20 0.35
LMNA P02545 1/20 0.35
S1PR2 O95136 1/20 0.34
S1PR1 P21453 1/20 0.34
S1PR3 Q99500 1/20 0.34
S1PR5 Q9H228 1/20 0.34
LPAR3 Q9UBY5 3/20 0.33
KDM4E B2RXH2 1/20 0.33
THRB P10828 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N,N-Dimethylethanaminium SCHEMBL9049890 1.00 FDPS (0.46) FDPSMMP2MMP1MMP3MMP8
N,N-Dimethylethanaminium SCHEMBL7539367 1.00 FDPS (0.46) FDPSMMP2MMP1MMP3MMP8
Phosphoric Acid SCHEMBL728521 0.83 MMP2 (0.43) FDPSMMP2MMP1MMP3MMP8
Phosphoric Acid SCHEMBL8778363 0.83 MMP2 (0.43) FDPSMMP2MMP1MMP3MMP8
Phosphoric Acid SCHEMBL1019439 0.79 FDPS (0.46) FDPSMMP2MMP1MMP3MMP8
Phosphoric Acid SCHEMBL192007 0.79 FDPS (0.46) FDPSMMP2MMP1MMP3MMP8
Phosphoric Acid SCHEMBL9359318 0.79 FDPS (0.46) FDPSMMP2MMP1MMP3MMP8
Phosphoric Acid SCHEMBL28801115 0.79 FDPS (0.46) FDPSMMP2MMP1MMP3MMP8
N,N-Dimethylethanaminium SCHEMBL22572517 0.79 PHGDH (0.33) FDPSMMP2MMP1MMP3MMP8
Phosphoric Acid SCHEMBL21359160 0.79 FDPS (0.46) FDPSMMP2MMP1MMP3MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106397133-A Synthetic method for metoprolol drug intermediate methyl phenylethyl ether 厦门安普顿信息科技有限公司 2017-02-15 CN disclosed
CN-105503543-A Synthetic method for medical intermediate methyl phenethyl ether of metoprolol CHENGDU CARDIFF TECH CO LTD 2016-04-20 CN disclosed
EP-0536147-B1 ANTISTATIC POLYOLEFIN FOAMS AND FILMS AND METHOD OF MAKING THE FOAM AND ANTISTATIC COMPOSITION DOW CHEMICAL CO (US) 1996-11-13 EP disclosed
EP-0536147-A4 ANTISTATIC POLYOLEFIN FOAMS AND FILMS AND METHOD OF MAKING THE FOAM AND ANTISTATIC COMPOSITION 1993-06-23 EP disclosed
EP-0536147-A1 ANTISTATIC POLYOLEFIN FOAMS AND FILMS AND METHOD OF MAKING THE FOAM AND ANTISTATIC COMPOSITION. DOW CHEMICAL CO (US) 1993-04-14 EP disclosed
US-5112528-A Quaternary Ammonium Salt, Partial Ester of Polyol with Fatty Acid THE DOW CHEMICAL COMPANY (US) 1992-05-12 US disclosed
US-5110841-A Synergistic mixture of quaternary ammonium compound and ester of fatty acid with polyol THE DOW CHEMICAL COMPANY (US) 1992-05-05 US disclosed
WO-1992000346-A1 ANTISTATIC POLYOLEFIN FOAMS AND FILMS AND METHOD OF MAKING THE FOAM AND ANTISTATIC COMPOSITION THE DOW CHEMICAL COMPANY (US) 1992-01-09 WO disclosed
US-5071884-A Mixing plastified polyolefin with partial ester of fatty acid and polyol, blowing agent, quaternary ammonium salt; foaming THE DOW CHEMICAL COMPANY (US) 1991-12-10 US disclosed
US-4605684-A QUATERNARY AMMONIUM COMPOUND AND PLASTICIZER ADDED BEFORE FOAMING; FLEXIBILITY GLENFED FINANCIAL CORPORATION 1986-08-12 US disclosed