Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 4/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28155734 | 0.82 | GABRA1 (0.38) | ALDH1A1CHKAPTPN1 | |
| SCHEMBL11700167 | 0.81 | MEN1 (0.40) | MEN1KMT2AHTTHSP90AA1ALDH1A1 | |
| SCHEMBL1254040 | 0.81 | ATP4A (0.44) | LMNASMN1; SMN2ALDH1A1MAPK1EGFR | |
| SCHEMBL16310159 | 0.78 | AOC3 (0.34) | SMN1; SMN2ALDH1A1ATP4AATP4B | |
| SCHEMBL9802567 | 0.76 | HSP90AA1 (0.44) | MEN1KMT2AHTTHSP90AA1CHKA | |
| SCHEMBL27610581 | 0.74 | AR (0.43) | MEN1KMT2AHTTLMNAHPGD | |
| SCHEMBL6141524 | 0.74 | TAAR1 (0.37) | MEN1KMT2AALDH1A1 | |
| SCHEMBL13068669 | 0.73 | NPSR1 (0.40) | KMT2AHTTALDH1A1NPSR1PTPN1 | |
| SCHEMBL7155151 | 0.73 | MEN1 (0.46) | MEN1KMT2AHTTLMNAHSP90AA1 | |
| SCHEMBL28291937 | 0.73 | PTPN1 (0.47) | HSP90AA1CHKAPTPN1HSP90AB1POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729464-A1 | 5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE, DAVIS & COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |