Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.33 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.33 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19661689 | 0.82 | TAAR1 (0.41) | TAAR1MEN1TNNI3TNNT2TNNC1 | |
| SCHEMBL1254040 | 0.80 | ATP4A (0.44) | MAPTALDH1A1CYP2D6 | |
| SCHEMBL16795582 | 0.77 | MAOA (0.43) | ALDH1A1CYP2D6 | |
| SCHEMBL2425306 | 0.77 | MEN1 (0.44) | TAAR1MEN1TNNI3TNNT2TNNC1 | |
| SCHEMBL16310159 | 0.77 | AOC3 (0.34) | MAPTALDH1A1 | |
| SCHEMBL6141114 | 0.76 | MEN1 (0.49) | TAAR1MEN1TNNI3TNNT2TNNC1 | |
| SCHEMBL9050053 | 0.74 | MEN1 (0.35) | MEN1KMT2AALDH1A1 | |
| SCHEMBL27610581 | 0.73 | AR (0.43) | MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8677186 | 0.72 | SLC6A4 (0.43) | MEN1KMT2AALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL2572183 | 0.70 | PYCR1 (0.43) | MEN1KMT2AALDH1A1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515940-A2 | AMINOALKOXY-FUNCTIONAL CHALCONES | Lica Pharmaceuticals A/S (DK) | 2005-03-23 | — | — | EP | disclosed |
| WO-2003097574-A2 | AMINOALKOXY-FUNCTIONAL CHALCONES | LICA PHARMACEUTICALS A/S (DK) | 2003-11-27 | — | — | WO | disclosed |