Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.61 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.61 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | IDH1 | O75874 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20504197 | 0.82 | CYP4A11 (0.66) | CYP4A11CYP4F2LOXL2IDH1ALDH1A1 | |
| SCHEMBL9343047 | 0.82 | CYP4A11 (0.53) | CYP4A11CYP4F2LOXL2IDH1ALDH1A1 | |
| SCHEMBL9343689 | 0.81 | CYP4A11 (0.52) | CYP4A11CYP4F2LOXL2ALDH1A1TP53 | |
| SCHEMBL8982437 | 0.79 | CYP4A11 (0.54) | CYP4A11CYP4F2LOXL2IDH1ALDH1A1 | |
| SCHEMBL9039166 | 0.78 | CYP4A11 (0.52) | CYP4A11CYP4F2LOXL2IDH1ALDH1A1 | |
| SCHEMBL10169575 | 0.77 | CYP4A11 (0.68) | CYP4A11CYP4F2LOXL2IDH1ALDH1A1 | |
| SCHEMBL10610477 | 0.77 | CYP4A11 (0.75) | CYP4A11CYP4F2LOXL2IDH1ALDH1A1 | |
| SCHEMBL1628660 | 0.77 | CYP4A11 (1.00) | CYP4A11CYP4F2LOXL2IDH1ALDH1A1 | |
| SCHEMBL10641751 | 0.77 | CYP4A11 (0.75) | CYP4A11CYP4F2LOXL2ALDH1A1TP53 | |
| SCHEMBL8044139 | 0.77 | CYP4A11 (0.75) | CYP4A11CYP4F2LOXL2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314280-B1 | Process for the preparation of fused pyridine compounds | UNIV PRINCETON (US) | 1996-02-21 | — | — | EP | disclosed |
| US-5473071-A | Process for the preparation of fused pyridine compounds | TRUSTEES OF PRINCETON UNIVERSITY (US) | 1995-12-05 | — | — | US | disclosed |
| US-4895946-A | Process for the preparation of fused pyridine compounds | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1990-01-23 | — | — | US | disclosed |
| EP-0314280-A2 | Process for the preparation of fused pyridine compounds | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1989-05-03 | — | — | EP | disclosed |