Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 5/20 | 1.00 |
| ▸ | CYP4F2 | P78329 | 4/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.58 |
| ▸ | DHODH | Q02127 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CKS1B | P61024 | 1/20 | 0.51 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2654656 | 0.98 | CYP4A11 (0.97) | CYP4A11CYP4F2POLBLOXL2DHODH | |
| SCHEMBL1796445 | 0.98 | CYP4A11 (0.97) | CYP4A11CYP4F2POLBLOXL2DHODH | |
| SCHEMBL2654036 | 0.98 | CYP4A11 (0.97) | CYP4A11CYP4F2POLBLOXL2DHODH | |
| SCHEMBL2653147 | 0.98 | CYP4A11 (0.97) | CYP4A11CYP4F2POLBLOXL2DHODH | |
| SCHEMBL2654777 | 0.95 | CYP4A11 (1.00) | CYP4A11CYP4F2POLBLOXL2DHODH | |
| 1,4-Butanediol SCHEMBL2722579 | 0.89 | CYP4A11 (0.79) | CYP4A11CYP4F2POLBLOXL2ALDH1A1 | |
| SCHEMBL2655571 | 0.87 | CYP4A11 (0.79) | CYP4A11CYP4F2POLBLOXL2ALDH1A1 | |
| SCHEMBL18106036 | 0.87 | CYP4A11 (0.79) | CYP4A11CYP4F2POLBLOXL2DHODH | |
| SCHEMBL8044139 | 0.86 | CYP4A11 (0.75) | CYP4A11CYP4F2LOXL2ALDH1A1MAPT | |
| SCHEMBL10641751 | 0.86 | CYP4A11 (0.75) | CYP4A11CYP4F2LOXL2DHODHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116606625-A | Moisture-heat-resistant polyurethane heat-conducting structural adhesive and preparation method thereof | 广东德聚技术股份有限公司 | 2023-08-18 | — | — | CN | claimed |
| EP-4692061-A1 | LOW-MOLECULAR-WEIGHT COMPOUND HAVING CEREBLON-BINDING ACTIVITY, AND USE THEREOF | Aevis Bio, Inc. (KR) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025262297-A1 | PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 | DARK BLUE THERAPEUTICS LTD (GB) | 2025-12-26 | — | — | WO | disclosed |
| EP-4667467-A1 | PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 | Dark Blue Therapeutics Ltd (GB) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024205319-A1 | LOW-MOLECULAR-WEIGHT COMPOUND HAVING CEREBLON-BINDING ACTIVITY, AND USE THEREOF | 주식회사 아이비스바이오 | 2024-10-03 | — | — | WO | disclosed |
| CN-116606625-A | Moisture-heat-resistant polyurethane heat-conducting structural adhesive and preparation method thereof | 广东德聚技术股份有限公司 | 2023-08-18 | — | — | CN | disclosed |
| US-11612662-B2 | Multi-arm polymeric prodrug conjugates of pemetrexed-based compounds | NEKTAR THERAPEUTICS (US) | 2023-03-28 | — | — | US | disclosed |
| US-20230091810-A1 | FIRST-IN-CLASS OF SHMT2 AND MTHFD2 INHIBITORS AS ANTITUMOR AGENTS | DUQUESNE UNIVERSITY OF THE HOLY SPIRIT | 2023-03-23 | — | — | US | disclosed |
| US-11565994-B2 | Inhibitors of histone lysine specific demethylase (LSD1) and histone deacetylases (HDACS) | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-01-31 | — | — | US | disclosed |
| US-11565994-B2 | Inhibitors of histone lysine specific demethylase (LSD1) and histone deacetylases (HDACS) | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-01-31 | — | — | US | disclosed |
| EP-0593603-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-04-27 | — | — | EP | disclosed |
| WO-1993000095-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-07 | — | — | WO | disclosed |
| US-4895946-A | Process for the preparation of fused pyridine compounds | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1990-01-23 | — | — | US | disclosed |
| EP-0162208-B1 | NOVEL N-SUBSTITUTED 3,4-DIHYDROPYRIMIDINE DERIVATIVES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS | SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) | 1989-11-23 | — | — | EP | disclosed |
| US-4871743-A | L-glutamic acid derivatives | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1989-10-03 | — | — | US | disclosed |
| EP-0325343-A2 | L-glutamic acid derivatives | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1989-07-26 | — | — | EP | disclosed |
| EP-0314280-A2 | Process for the preparation of fused pyridine compounds | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1989-05-03 | — | — | EP | disclosed |
| US-4683234-A | HYPOTENSIVE AGENTS, ANTI-ANGINA | SUNTORY LIMITED (JP) | 1987-07-28 | — | — | US | disclosed |
| EP-0162208-A2 | Novel N-substituted 3,4-dihydropyrimidine derivatives, processes for preparing them and pharmaceutical compositions | SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) | 1985-11-27 | — | — | EP | disclosed |
| US-4024173-A | Process for the manufacture of cyclohexene dicarboxylic acid esters | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11612662-B2 | Multi-arm polymeric prodrug conjugates of pemetrexed-based compounds | PAICS, MTHFD2, MTHFD1 | CYP4A11 3483/4885CYP4F2 2890/4885POLB 132/4885 |
| US-11565994-B2 | Inhibitors of histone lysine specific demethylase (LSD1) and histone deacetylases (HDACS) | KDM1B, KDM2A, EHMT2 | CYP4A11 3135/4885CYP4F2 1361/4885POLB 1446/4885 |
| US-20230091810-A1 | FIRST-IN-CLASS OF SHMT2 AND MTHFD2 INHIBITORS AS ANTITUMOR AGENTS | MTHFD1, SHMT1, SHMT2 | CYP4A11 816/4885CYP4F2 37/4885POLB 2204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.