Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | VHL | P40337 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14962448 | 0.80 | VHL (0.35) | MEN1ALDH1A1KMT2AKDM4EPKM | |
| SCHEMBL14962396 | 0.80 | SLC6A3 (0.39) | TAAR1MEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL15615745 | 0.77 | SLC6A2 (0.40) | MEN1ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL12179777 | 0.77 | TRPA1 (0.40) | TAAR1VHLP2RX7 | |
| SCHEMBL9051447 | 0.76 | CYP2C19 (0.42) | MEN1ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL8632334 | 0.75 | ALOX5 (0.33) | KDM4EPKMCYP2D6 | |
| SCHEMBL15213178 | 0.73 | KDM4E (0.38) | MEN1ALDH1A1KMT2AKDM4EPKM | |
| SCHEMBL259320 | 0.73 | KDM4E (0.38) | MEN1ALDH1A1KMT2AKDM4EPKM | |
| SCHEMBL23384732 | 0.72 | KDM4E (0.37) | TAAR1MEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL8200743 | 0.72 | KDM4E (0.44) | MEN1ALDH1A1KMT2AKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707584-A1 | NOVEL (1-HETEROAZOLYL-1-HETEROCYCLYL)ALKANE DERIVATIVES AND THEIR USE AS NEUROPROTECTIVE AGENTS | Astra Aktiebolag (SE) | 1996-04-24 | — | — | EP | disclosed |