Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GART | P22102 | 5/20 | 0.48 |
| ▸ | DHFR | P00374 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ATIC | P31939 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050424 | 1.00 | GART (0.48) | GARTDHFRKDM4EALDH1A1HPGD | |
| SCHEMBL9048289 | 0.96 | GART (0.44) | GARTDHFRKDM4EALDH1A1HPGD | |
| SCHEMBL9048299 | 0.96 | GART (0.44) | GARTDHFRKDM4EALDH1A1HPGD | |
| SCHEMBL9534079 | 0.92 | GART (0.49) | GARTDHFRKDM4EALDH1A1HPGD | |
| SCHEMBL9534086 | 0.92 | GART (0.49) | GARTDHFRKDM4EALDH1A1HPGD | |
| SCHEMBL9209872 | 0.91 | GART (0.38) | GARTDHFRKDM4EALDH1A1HPGD | |
| SCHEMBL9383614 | 0.88 | GART (0.56) | GARTDHFRKDM4EALDH1A1HPGD | |
| SCHEMBL9383606 | 0.88 | GART (0.56) | GARTDHFRKDM4EALDH1A1HPGD | |
| SCHEMBL9215054 | 0.88 | DHFR (0.37) | GARTDHFRKDM4EALDH1A1HPGD | |
| SCHEMBL10479162 | 0.87 | KDM4E (0.37) | GARTDHFRKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314280-B1 | Process for the preparation of fused pyridine compounds | UNIV PRINCETON (US) | 1996-02-21 | — | — | EP | disclosed |
| US-5473071-A | Process for the preparation of fused pyridine compounds | TRUSTEES OF PRINCETON UNIVERSITY (US) | 1995-12-05 | — | — | US | disclosed |
| EP-0265126-B1 | Process for the preparation of fused pyridine compounds | UNIV PRINCETON (US) | 1994-04-13 | — | — | EP | disclosed |
| US-4988813-A | Process for the preparation of fused pyridine compounds | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1991-01-29 | — | — | US | disclosed |
| US-4902796-A | 6-alkenyl and ethynyl derivatives of 2-amino-4-hydroxypyrido[2,3-d]pyrimidines | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1990-02-20 | — | — | US | disclosed |
| US-4895946-A | Process for the preparation of fused pyridine compounds | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1990-01-23 | — | — | US | disclosed |
| US-4818819-A | Process for the preparation of fused pyridine compounds | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1989-04-04 | — | — | US | disclosed |
| EP-0265126-A2 | Process for the preparation of fused pyridine compounds | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1988-04-27 | — | — | EP | disclosed |