Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050732 | 0.89 | DRD2 (0.61) | DRD2ADRA1ADRD3DRD4CYP1A2 | |
| SCHEMBL9052696 | 0.89 | DRD2 (0.46) | DRD2ADRA1ADRD3DRD4CYP1A2 | |
| SCHEMBL9053113 | 0.89 | DRD2 (0.56) | DRD2ADRA1ADRD3DRD4CYP1A2 | |
| SCHEMBL9052324 | 0.89 | DRD2 (0.61) | DRD2ADRA1ADRD3DRD4CYP1A2 | |
| SCHEMBL8986025 | 0.89 | DRD2 (0.56) | DRD2ADRA1AHTR1AOPRM1OPRK1 | |
| SCHEMBL9052266 | 0.87 | MEN1 (0.58) | CYP3A4HTR1AMEN1KMT2ASIGMAR1 | |
| SCHEMBL9052744 | 0.86 | DRD2 (0.59) | DRD2ADRA1ADRD3DRD4CYP1A2 | |
| SCHEMBL9052260 | 0.86 | OPRM1 (0.46) | DRD2ADRA1ADRD3DRD4CYP3A4 | |
| SCHEMBL9052350 | 0.85 | KMT2A (0.53) | DRD2ADRA1AHTR1AMEN1KMT2A | |
| SCHEMBL9055896 | 0.81 | OPRM1 (0.44) | DRD2DRD3DRD4HTR1AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002250-A1 | HALOPERIDOL ANALOGS AND THE USE THEREOF | ACEA PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |