Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056541 | 0.93 | FFAR1 (0.41) | KDM4EFFAR1MEN1KMT2ASLC2A1 | |
| SCHEMBL9052107 | 0.81 | NR3C1 (0.39) | KDM4EFFAR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9050102 | 0.78 | NR3C1 (0.45) | KDM4EFFAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL177838 | 0.67 | KDM4E (1.00) | KDM4EFFAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL8644568 | 0.66 | AKR1C3 (0.39) | — | |
| SCHEMBL7044513 | 0.65 | MAOB (0.79) | KDM4EMEN1KMT2AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL8351982 | 0.63 | KMT2A (0.39) | MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9054914 | 0.61 | AKR1C3 (0.44) | KDM4E | |
| SCHEMBL13240466 | 0.60 | TP53 (0.61) | KDM4EMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11265703 | 0.60 | MAOB (0.79) | MAOAMAOBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996037204-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-11-28 | — | — | WO | disclosed |