Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 2/20 | 0.36 |
| ▸ | FNTB | P49356 | 2/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9051254 | 0.93 | KDM4E (0.46) | FFAR1CETPSLC2A1ALDH1A1KDM4E | |
| SCHEMBL9052107 | 0.78 | NR3C1 (0.39) | FFAR1CETPALDH1A1KDM4E | |
| SCHEMBL31504019 | 0.68 | KDM4E (0.72) | FFAR1ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL7993232 | 0.65 | MEN1 (0.63) | FFAR1ALDH1A1KDM4EMAOBMAPT | |
| SCHEMBL3635549 | 0.65 | MAPT (0.61) | FFAR1ALDH1A1KDM4EMAOAMAOB | |
| SCHEMBL8642101 | 0.64 | FFAR1 (0.45) | FFAR1ALDH1A1KDM4EMAOAMAOB | |
| SCHEMBL13240465 | 0.63 | LOXL2 (0.55) | ALDH1A1MAOAMAOBMAPTTP53 | |
| SCHEMBL12579455 | 0.63 | MEN1 (0.56) | FFAR1ALDH1A1KDM4EMAOAMAOB | |
| SCHEMBL2191978 | 0.63 | MAPT (0.49) | ALDH1A1MAOAMAOBMAPTMEN1 | |
| SCHEMBL9081386 | 0.63 | ALDH1A1 (0.61) | FFAR1SLC2A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996037204-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-11-28 | — | — | WO | disclosed |