Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9052107 | 0.92 | NR3C1 (0.39) | NR3C1GRIN1GRIN2BALDH1A1LMNA | |
| SCHEMBL9051254 | 0.78 | KDM4E (0.46) | ALDH1A1LMNASMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL9056541 | 0.76 | FFAR1 (0.41) | ALDH1A1MEN1KMT2ACETPMAPT | |
| SCHEMBL457863 | 0.64 | HSPB1 (0.68) | NR3C1ALDH1A1LMNASMN1; SMN2CRHBP | |
| SCHEMBL9351277 | 0.63 | CYP19A1 (0.46) | ALDH1A1LMNAKMT2AKCNH2MAPT | |
| SCHEMBL11170684 | 0.63 | CRHBP (0.66) | NR3C1ALDH1A1SMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL27949945 | 0.63 | CRHBP (0.57) | NR3C1ALDH1A1LMNASMN1; SMN2CRHBP | |
| SCHEMBL9081359 | 0.61 | PTPRF (0.58) | NR3C1ALDH1A1LMNASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL8351982 | 0.61 | KMT2A (0.39) | LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL6733709 | 0.60 | MAPT (0.66) | LMNAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996037204-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-11-28 | — | — | WO | disclosed |