Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8670678 | 0.90 | MAOA (0.55) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11538421 | 0.88 | SLC18A3 (0.56) | SLC18A3OPRK1HDAC6HDAC3HDAC4 | |
| SCHEMBL27373891 | 0.88 | SLC18A3 (0.56) | SLC18A3OPRK1HDAC6HDAC3HDAC4 | |
| SCHEMBL1581171 | 0.88 | OPRK1 (0.48) | SLC18A3OPRK1HDAC6HDAC3HDAC4 | |
| SCHEMBL25242855 | 0.87 | HDAC3 (0.66) | SLC18A3OPRK1HDAC6HDAC3HDAC4 | |
| SCHEMBL10724420 | 0.87 | HDAC3 (0.62) | SLC18A3OPRK1HDAC6HDAC3HDAC4 | |
| SCHEMBL1582103 | 0.87 | FAAH (0.52) | SLC18A3OPRK1HDAC6FAAHKDM1A | |
| SCHEMBL10720231 | 0.87 | CYP2C9 (0.58) | SLC18A3OPRK1HDAC6HDAC3HDAC4 | |
| SCHEMBL8905029 | 0.85 | HDAC6 (0.55) | SLC18A3OPRK1HDAC6HDAC3HDAC4 | |
| SCHEMBL8904149 | 0.85 | HDAC6 (0.55) | SLC18A3OPRK1HDAC6HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996041802-A1 | NOVEL HETEROAROMATIC PIPERAZINES FOR USE AS DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1996-12-27 | — | — | WO | claimed |
| WO-1996041802-A1 | NOVEL HETEROAROMATIC PIPERAZINES FOR USE AS DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1996-12-27 | — | — | WO | disclosed |