SCHEMBL9051258

SCHEMBL9051258

O=C(O)C1COC(Cc2ccccc2)CO1

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.42
GRM2 Q14416 1/20 0.39
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15844495 0.83 MGLL (0.41) MGLLSLC6A2SLC6A4SLC6A3
SCHEMBL51254 0.82 SLC6A2 (0.50) GRM2SLC6A2SLC6A4SLC6A3
SCHEMBL873444 0.82 SLC6A2 (0.50) GRM2SLC6A2SLC6A4SLC6A3
SCHEMBL2186411 0.82 SLC6A2 (0.50) GRM2SLC6A2SLC6A4SLC6A3
Methane SCHEMBL28820455 0.80 SLC6A2 (0.48) GRM2SLC6A2SLC6A4SLC6A3
Water SCHEMBL27572757 0.80 SLC6A2 (0.48) GRM2SLC6A2SLC6A4SLC6A3
SCHEMBL6664494 0.79 SLC6A2 (0.42) MGLLGRM2SLC6A2SLC6A4SLC6A3
Acrylic Acid SCHEMBL8176236 0.78 MGLL (0.43) MGLLGRM2SLC6A2SLC6A4SLC6A3
Ethylene SCHEMBL28205448 0.78 SLC6A2 (0.47) GRM2SLC6A2SLC6A4SLC6A3
SCHEMBL25075458 0.77 ALDH1A1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0724580-A1 BENZANILIDE DERIVATIVES AS 5HT-1D RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 1996-08-07 EP disclosed
WO-1995011243-A1 BENZANILIDE DERIVATIVES AS 5HT-1D RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 1995-04-27 WO disclosed