Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8849143 | 0.77 | GBA1 (0.43) | ALDH1A1CYP19A1GBA1LTB4RLTB4R2 | |
| SCHEMBL9051258 | 0.77 | MGLL (0.42) | — | |
| SCHEMBL11624498 | 0.74 | FFAR3 (0.31) | — | |
| SCHEMBL31629437 | 0.73 | CTSL (0.44) | ALDH1A1 | |
| SCHEMBL19403045 | 0.73 | CTSL (0.44) | ALDH1A1 | |
| SCHEMBL7810455 | 0.73 | GRIN2B (0.46) | TACR3L3MBTL1GBA1MEN1KMT2A | |
| SCHEMBL14478960 | 0.73 | BCHE (0.46) | ALDH1A1 | |
| SCHEMBL402480 | 0.73 | BCHE (0.46) | ALDH1A1 | |
| SCHEMBL10955906 | 0.72 | GBA1 (0.42) | ALDH1A1GBA1 | |
| SCHEMBL21987176 | 0.72 | PDK1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023287-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS SEROTONIN (5-HT) 5-HT2A AND 5-HT2C RECEPTOR POSITIVE ALLOSTERIC MODULATORS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-02-23 | — | — | WO | disclosed |