Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 14/20 | 0.68 |
| ▸ | RARG | P13631 | 13/20 | 0.68 |
| ▸ | RARA | P10276 | 13/20 | 0.68 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.68 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.68 |
| ▸ | RXRA | P19793 | 9/20 | 0.61 |
| ▸ | RXRB | P28702 | 7/20 | 0.61 |
| ▸ | RXRG | P48443 | 5/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31191789 | 1.00 | RARB (0.68) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL9047780 | 0.87 | RARB (0.51) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL6915033 | 0.85 | RXRA (0.64) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL9050990 | 0.84 | RARB (0.47) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL7761329 | 0.82 | RARB (0.80) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL2391376 | 0.82 | RARB (1.00) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL29440075 | 0.80 | RXRA (0.68) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL2128581 | 0.80 | RXRA (0.68) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL29827631 | 0.80 | RARB (0.81) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL846110 | 0.80 | RARB (0.81) | RARBRARGRARACYP26A1CYP26B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11911356-B2 | Regulation of mutant TERT by BRAF V600E/map kinase pathway through FOS/GABP in human cancer | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-02-27 | — | — | US | claimed |
| US-20200323805-A1 | REGULATION OF MUTANT TERT BY BRAF V600E/MAP KINASE PATHWAY THROUGH FOS/GABP IN HUMAN CANCER | THE JOHNS HOPKINS UNIVERSITY | 2020-10-15 | — | — | US | claimed |
| US-20250290152-A1 | GENETIC TRIO OF BRAF AND TERT MUTATIONS AND RS2853669TT IN PAPILLARY THYROID CANCER AGGRESSIVENESS | THE JOHNS HOPKINS UNIVERSITY | 2025-09-18 | — | — | US | disclosed |
| US-11911356-B2 | Regulation of mutant TERT by BRAF V600E/map kinase pathway through FOS/GABP in human cancer | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-02-27 | — | — | US | disclosed |
| US-20200323805-A1 | REGULATION OF MUTANT TERT BY BRAF V600E/MAP KINASE PATHWAY THROUGH FOS/GABP IN HUMAN CANCER | THE JOHNS HOPKINS UNIVERSITY | 2020-10-15 | — | — | US | disclosed |
| WO-1995033745-A9 | NOVEL COMPOUNDS USEFUL IN MODULATING GENE EXPRESSION OF RETINOID RESPONSIVE GENES AND/OR HAVING ANTI-AP-1 ACTIVITY | — | 1996-01-18 | — | — | WO | disclosed |
| WO-1995033745-A2 | NOVEL COMPOUNDS USEFUL IN MODULATING GENE EXPRESSION OF RETINOID RESPONSIVE GENES AND/OR HAVING ANTI-AP-1 ACTIVITY | SRI INTERNATIONAL (US) | 1995-12-14 | — | — | WO | disclosed |