Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 5/20 | 0.41 |
| ▸ | ITK | Q08881 | 10/20 | 0.39 |
| ▸ | INSR | P06213 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10047553 | 0.81 | TP53 (0.46) | MLNRITKINSRTP53 | |
| SCHEMBL905145 | 0.80 | MLNR (0.63) | MLNR | |
| SCHEMBL905124 | 0.78 | MLNR (0.64) | MLNR | |
| SCHEMBL905146 | 0.78 | MLNR (0.43) | MLNR | |
| SCHEMBL905131 | 0.71 | TP53 (0.41) | ITKTP53 | |
| SCHEMBL905136 | 0.70 | MLNR (0.71) | MLNR | |
| SCHEMBL11938472 | 0.70 | PKM (0.47) | ITKTP53 | |
| SCHEMBL9001804 | 0.68 | HSD17B1 (0.49) | ITKINSR | |
| SCHEMBL905171 | 0.67 | CNR2 (0.48) | ITKTP53 | |
| SCHEMBL7051990 | 0.66 | CNR2 (0.46) | MLNRITKINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012043445-A1 | CYCLOHEXANE DERIVATIVE COMPOUND | 第一三共株式会社 (JP) | 2012-04-05 | — | — | WO | disclosed |