Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLQ | O75417 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10047068 | 0.90 | CNR2 (0.44) | CNR2CNR1TP53RAB9AKDM4E | |
| SCHEMBL905174 | 0.85 | ALDH1A1 (0.41) | CNR2CNR1TP53ALDH1A1NR1H4 | |
| SCHEMBL10047553 | 0.85 | TP53 (0.46) | CNR2CNR1TP53ITK | |
| SCHEMBL905131 | 0.81 | TP53 (0.41) | CNR2CNR1TP53ITKKDM4E | |
| SCHEMBL5085615 | 0.78 | CNR2 (0.53) | CNR2CNR1ITKRAB9AACHE | |
| SCHEMBL7141111 | 0.74 | HTT (0.63) | CNR2CNR1TP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL29031636 | 0.72 | CNR2 (0.49) | CNR2CNR1TP53SMN1; SMN2KDM4E | |
| SCHEMBL1341177 | 0.69 | CNR2 (0.49) | CNR2CNR1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL2938750 | 0.68 | MLYCD (0.60) | CNR2CNR1SMN1; SMN2LMNA | |
| SCHEMBL905141 | 0.67 | MLNR (0.41) | TP53ITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012043445-A1 | CYCLOHEXANE DERIVATIVE COMPOUND | 第一三共株式会社 (JP) | 2012-04-05 | — | — | WO | disclosed |