Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050614 | 0.96 | TP53 (0.44) | CYP4A11CYP4F2TP53CYP3A4KCNH2 | |
| SCHEMBL9050867 | 0.88 | RARB (0.41) | SMN1; SMN2 | |
| SCHEMBL9052458 | 0.83 | GART (0.44) | TP53SMN1; SMN2DHFR | |
| SCHEMBL9339199 | 0.77 | DHFR (0.54) | CYP4A11CYP4F2TP53CYP3A4TLR8 | |
| SCHEMBL9339245 | 0.75 | CYP4A11 (0.55) | CYP4A11CYP4F2TP53CYP3A4TLR8 | |
| SCHEMBL9341073 | 0.74 | CYP4A11 (0.53) | CYP4A11CYP4F2TP53CYP3A4TLR8 | |
| SCHEMBL9844981 | 0.73 | EGFR (0.46) | CYP4A11CYP4F2TP53CYP3A4TLR8 | |
| SCHEMBL9844803 | 0.72 | TP53 (0.46) | CYP4A11CYP4F2TP53CYP3A4TLR8 | |
| SCHEMBL9844832 | 0.72 | TP53 (0.44) | CYP4A11CYP4F2TP53CYP3A4KCNH2 | |
| SCHEMBL9844887 | 0.72 | CYP3A4 (0.44) | CYP4A11CYP4F2TP53CYP3A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314280-B1 | Process for the preparation of fused pyridine compounds | UNIV PRINCETON (US) | 1996-02-21 | — | — | EP | disclosed |
| US-4895946-A | Process for the preparation of fused pyridine compounds | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1990-01-23 | — | — | US | disclosed |