Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.66 |
| ▸ | SRC | P12931 | 1/20 | 0.66 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.52 |
| ▸ | TUBB | P07437 | 1/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.52 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.52 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.52 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.52 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.52 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.52 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.52 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29988920 | 0.82 | EGFR (0.66) | EGFRSRCTUBB4ATUBBTUBA3C | |
| SCHEMBL9051008 | 0.82 | TUBB4A (0.46) | EGFRSRCTUBB4ATUBBTUBA3C | |
| SCHEMBL9051398 | 0.82 | TUBB4A (0.46) | EGFRSRCTUBB4ATUBBTUBA3C | |
| SCHEMBL9062568 | 0.82 | TUBB4A (0.46) | EGFRSRCTUBB4ATUBBTUBA3C | |
| SCHEMBL18160178 | 0.81 | EGFR (0.68) | EGFRSRCTUBB4ATUBBTUBA3C | |
| SCHEMBL5960508 | 0.81 | EGFR (0.56) | EGFRSRCCNR1ALDH1A1IDO1 | |
| SCHEMBL4189420 | 0.81 | EGFR (0.56) | EGFRSRCCNR1ALDH1A1IDO1 | |
| SCHEMBL10475669 | 0.80 | TUBB4A (0.49) | EGFRSRCTUBB4ATUBBTUBA3C | |
| SCHEMBL8780773 | 0.80 | CNR1 (0.51) | EGFRSRCTUBB4ATUBBTUBA3C | |
| SCHEMBL5788230 | 0.80 | TUBB4A (0.58) | EGFRSRCTUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734386-A1 | PLATELET ACTIVATING FACTOR ANTAGONISTS: IMIDAZOPYRIDINE INDOLES | Abbott Laboratories (US) | 1996-10-02 | — | — | EP | disclosed |
| WO-1995016687-A1 | PLATELET ACTIVATING FACTOR ANTAGONISTS: IMIDAZOPYRIDINE INDOLES | ABBOTT LABORATORIES (US) | 1995-06-22 | — | — | WO | disclosed |