SCHEMBL8780773

SCHEMBL8780773

Cc1c(S(=O)(=O)c2ccccc2)[nH]c2ccccc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 9/20 0.51
DAO P14920 1/20 0.49
DDO Q99489 1/20 0.49
AHR P35869 1/20 0.48
TUBB4A P04350 1/20 0.48
TUBB P07437 1/20 0.48
TUBA3C P0DPH7 1/20 0.48
TUBA1B P68363 1/20 0.48
TUBA4A P68366 1/20 0.48
TUBB4B P68371 1/20 0.48
TUBB3 Q13509 1/20 0.48
TUBB2A Q13885 1/20 0.48
TUBB8 Q3ZCM7 1/20 0.48
TUBA3E Q6PEY2 1/20 0.48
TUBA1A Q71U36 1/20 0.48
TUBA1C Q9BQE3 1/20 0.48
TUBB6 Q9BUF5 1/20 0.48
TUBB2B Q9BVA1 1/20 0.48
TUBB1 Q9H4B7 1/20 0.48
EGFR P00533 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9017539 0.80 AHR (0.59) CNR1DAODDOAHRGAA
SCHEMBL9051693 0.80 EGFR (0.66) CNR1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL7835359 0.79 HTR6 (0.43) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL3647177 0.79 HTR6 (0.43) CNR1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL4238498 0.79 CNR1 (0.52) CNR1DAODDOAHRMAPT
SCHEMBL5665323 0.78 MEN1 (0.43) AHRTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL30542066 0.78 MEN1 (0.43) AHRTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL3644543 0.78 PTGS2 (0.54) EGFRMAPTGAAALDH1A1HPGD
SCHEMBL28165688 0.78 KDM4E (0.54) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
(Phenylsulfonyl)Benzene SCHEMBL17092887 0.77 ALDH1A1 (0.61) AHRTUBB4ATUBBTUBA3CTUBA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0770085-A1 HETEROAROMATIC DIPHOSPHINES AS CHIRAL LIGANDS ITALFARMACO SUD S.p.A. (IT) 1997-05-02 EP disclosed
WO-1996001831-A1 HETEROAROMATIC DIPHOSPHINES AS CHIRAL LIGANDS ITALFARMACO SUD S.P.A. (IT) 1996-01-25 WO disclosed