Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 6/20 | 0.32 |
| ▸ | CA2 | P00918 | 6/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.30 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9051756 | 0.86 | KMT2A (0.40) | MEN1RAB9AKMT2AALDH1A1MAPT | |
| SCHEMBL9062344 | 0.85 | TSHR (0.36) | POLBL3MBTL1ALDH1A1MAPTLMNA | |
| SCHEMBL9754226 | 0.67 | RAB9A (0.58) | POLBMEN1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL11573483 | 0.62 | MAPT (0.42) | POLBMEN1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL1320586 | 0.61 | KDM4E (0.36) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL14677858 | 0.59 | POLB (0.58) | POLBCA1CA2MEN1RAB9A | |
| SCHEMBL8877167 | 0.58 | FABP4 (0.66) | POLBMEN1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL7098921 | 0.58 | CYP3A4 (0.69) | CA2MEN1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL19408173 | 0.57 | POLB (0.70) | POLBMEN1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL9621530 | 0.57 | MEN1 (0.83) | POLBMEN1RAB9AKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996040141-A1 | 4,5-BRIDGED QUINOXALINEDIONES AND QUINOLONES AND THE USE THEREOF AS EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ACEA PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |