Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GLS | O94925 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1037707 | 0.78 | MAPK8 (0.66) | KMT2AMAPK8MAPK10MEN1MAPK9 | |
| SCHEMBL9050785 | 0.76 | MAPK8 (0.64) | KMT2AMAPK8MAPK10MEN1MAPK9 | |
| SCHEMBL31400055 | 0.75 | HPGD (0.54) | KMT2AMAPK8MAPK10MEN1HPGD | |
| SCHEMBL27603123 | 0.75 | HPGD (0.54) | KMT2AMAPK8MAPK10MEN1MAPK9 | |
| SCHEMBL6169172 | 0.73 | MEN1 (0.83) | KMT2AMEN1HPGDGAAHDAC1 | |
| SCHEMBL4607222 | 0.72 | KMT2A (0.46) | KMT2AHPGDALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9049807 | 0.72 | CYP1A2 (0.56) | MAPK8MAPK10MAPK9HPGDGAA | |
| SCHEMBL28577453 | 0.69 | MEN1 (0.74) | KMT2AMEN1GAAHDAC1HDAC8 | |
| SCHEMBL13936057 | 0.69 | KDM4E (0.74) | KMT2AMAPK8MAPK10MEN1MAPK9 | |
| SCHEMBL13715870 | 0.69 | SMN1; SMN2 (0.58) | KMT2AALDH1A1SMN1; SMN2L3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717044-A1 | Thienopyridone derivatives, their preparation and their use as NMDA-receptor antagonists | MERCK PATENT GmbH (DE) | 1996-06-19 | — | — | EP | disclosed |