Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.70 |
| ▸ | DRD3 | P35462 | 4/20 | 0.63 |
| ▸ | TACR2 | P21452 | 1/20 | 0.52 |
| ▸ | TACR1 | P25103 | 1/20 | 0.52 |
| ▸ | TACR3 | P29371 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9052499 | 0.92 | DRD2 (0.73) | DRD2DRD3HTR2A | |
| SCHEMBL9052179 | 0.88 | DRD2 (0.67) | DRD2DRD3 | |
| SCHEMBL9051743 | 0.86 | DRD2 (0.66) | DRD2DRD3 | |
| SCHEMBL11742946 | 0.84 | DRD2 (0.78) | DRD2DRD3ADRA1AHTR1AHTR2A | |
| SCHEMBL11065503 | 0.83 | OPRM1 (0.53) | TACR2TACR1TACR3ADRA1AHTR7 | |
| SCHEMBL6643987 | 0.83 | OPRM1 (0.53) | TACR2TACR1TACR3ADRA1AHTR7 | |
| Hydrochloric Acid SCHEMBL11746185 | 0.83 | DRD2 (0.76) | DRD2DRD3ADRA1AHTR1AHTR2A | |
| SCHEMBL8986029 | 0.83 | DRD2 (1.00) | DRD2DRD3TACR1ADRA1AHTR1A | |
| SCHEMBL9052123 | 0.82 | DRD2 (0.74) | DRD2DRD3ADRA1AHTR1AHTR2A | |
| SCHEMBL10838283 | 0.81 | DRD3 (0.62) | DRD2DRD3TACR2TACR1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002250-A1 | HALOPERIDOL ANALOGS AND THE USE THEREOF | ACEA PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |