Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.53 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | TACR2 | P21452 | 2/20 | 0.52 |
| ▸ | TACR1 | P25103 | 2/20 | 0.52 |
| ▸ | TACR3 | P29371 | 2/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6643987 | 0.86 | OPRM1 (0.53) | OPRM1KCNA3HTR7TACR2TACR1 | |
| SCHEMBL917838 | 0.83 | OPRM1 (0.50) | OPRM1KCNA3HTR7TACR2TACR1 | |
| SCHEMBL9052124 | 0.83 | DRD2 (0.70) | HTR7TACR2TACR1TACR3ADRA1A | |
| SCHEMBL5330651 | 0.81 | CYP2D6 (0.61) | OPRM1KCNA3TACR2TACR1TACR3 | |
| SCHEMBL8440281 | 0.81 | OPRM1 (0.71) | OPRM1KCNA3OPRD1OPRK1ADRA1A | |
| SCHEMBL27651992 | 0.81 | GAA (0.52) | OPRM1KCNA3HTR7TACR2TACR1 | |
| SCHEMBL11721858 | 0.80 | AKR1C1 (0.54) | OPRM1KCNA3OPRD1OPRK1 | |
| SCHEMBL5848377 | 0.80 | OPRD1 (0.54) | OPRM1HTR7OPRD1OPRK1ADRA1A | |
| SCHEMBL8324812 | 0.79 | OPRM1 (0.63) | OPRM1OPRD1OPRK1ADRA1A | |
| SCHEMBL9052499 | 0.78 | DRD2 (0.73) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |